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KMID : 0931320130130020091
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대한상부위장관.헬리코박터학회지
2013 Volume.13 No. 2 p.91 ~ p.94
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Intestinal Metaplasia: Reversible after Treatment?
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Lee Si-Hyung
Jang Byung-Ik
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Abstract
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Intestinal metaplasia is often found in the clinical situation in Korea and was reported as a pre-cancerous lesion by several previous studies. Intestinal metaplasia is mainly caused by infection of Helicobacter pylori, but whether intestinal metaplasia improves or reverses after eradication of H. pylori has not been agreed upon. Most randomized clinical studies reported that intestinal metaplasia improved or did not progress after H. pylori eradication therapy. But, infection rates and antibiotic resistance rates of H. pylori infection and the prevalence of intestinal metaplasia varies according to the region and race, therefore large prospective randomized studies are needed before we can reach any conclusions.
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KEYWORD
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Intestinal metaplasia, Helicobacter pylori, Therapeutics
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